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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
10.91
Human Site:
S521
Identified Species:
20
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S521
E
D
S
E
N
F
P
S
S
S
K
K
S
E
E
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S521
E
D
S
E
N
F
P
S
S
S
K
K
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S521
E
D
S
K
N
F
P
S
S
S
K
K
S
E
E
Dog
Lupus familis
XP_537198
743
82483
D521
D
G
E
N
F
P
P
D
S
K
K
S
E
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
G521
D
N
G
S
F
P
A
G
S
N
K
P
E
E
W
Rat
Rattus norvegicus
Q5M9F8
807
89107
H555
A
E
I
E
K
D
V
H
A
A
S
S
P
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
A1146
F
Q
D
S
P
F
G
A
E
A
V
G
L
A
V
Chicken
Gallus gallus
NP_001012613
698
77220
V501
G
S
M
G
P
Y
F
V
E
R
D
V
D
E
K
Frog
Xenopus laevis
Q561M0
827
91284
S612
P
D
T
V
P
S
P
S
A
P
P
A
A
S
T
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
E522
E
S
R
K
S
N
G
E
V
R
T
D
E
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
K488
P
D
G
G
E
D
E
K
L
R
L
N
S
N
E
Honey Bee
Apis mellifera
XP_001123124
613
70111
G419
G
A
A
T
V
I
G
G
K
R
G
K
L
F
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
R533
M
R
I
K
N
E
Q
R
R
R
E
R
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
93.3
26.6
N.A.
20
6.6
N.A.
6.6
6.6
20
6.6
N.A.
20
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
40
26.6
N.A.
20
20
40
26.6
N.A.
20
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
8
8
16
16
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
39
8
0
0
16
0
8
0
0
8
8
8
8
0
% D
% Glu:
31
8
8
24
8
8
8
8
16
0
8
0
31
54
31
% E
% Phe:
8
0
0
0
16
31
8
0
0
0
0
0
0
8
0
% F
% Gly:
16
8
16
16
0
0
24
16
0
0
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
24
8
0
0
8
8
8
39
31
0
0
16
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
8
0
16
0
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
31
8
0
0
0
8
0
8
0
8
0
% N
% Pro:
16
0
0
0
24
16
39
0
0
8
8
8
8
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
0
8
8
39
0
8
0
0
0
% R
% Ser:
0
16
24
16
8
8
0
31
39
24
8
16
31
8
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
24
% T
% Val:
0
0
0
8
8
0
8
8
8
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _